Until recently, cytotoxic chemotherapy, surgery, radiotherapy and targeted therapy were the pillars of cancer treatment. Immunotherapy has now become the fifth pillar of oncologic care, but not without obstacles.
The Tumor Microenvironment is a reservoir of these obstacles tipping the scales towards the immune escape of tumors. The Tumor Microenvironment also provides rational targets for small molecule inhibition through which immunomodulation can occur and Bugworks is tapping into this potential to increase the response rate through DARE.
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