• Anti-Microbial susceptibility of Bugworks Lead compounds against recent clinical isolates

  • Structural biology of efflux pumps in gram negative

  • Structural biology of targets implied in Bugworks Drug Discovery

  • Antimicrobial pharmacokinetics and pharmacodynamics of Bugworks Lead compounds

  • Efficacy in specialized in vivo infection models

  • Bio-threat pathogen studies

  • Cystic fibrosis model